SCHEMBL2321979

SCHEMBL2321979

CC(=O)N1CCN(CCCCOc2ccc(NC(=O)NC34CC5CC(CC(C5)C3)C4)cc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12932148 0.83 EPHX2 (1.00) EPHX2
SCHEMBL12932214 0.80 EPHX2 (0.90) EPHX2
SCHEMBL27853348 0.78 EPHX2 (1.00) EPHX2
SCHEMBL14006285 0.77 EPHX2 (0.62) EPHX2
SCHEMBL3937582 0.77 EPHX2 (0.70) EPHX2
SCHEMBL27870233 0.76 EPHX2 (0.79) EPHX2
SCHEMBL12932045 0.75 EPHX2 (1.00) EPHX2
SCHEMBL27853373 0.75 EPHX2 (1.00) EPHX2
SCHEMBL27853337 0.75 EPHX2 (1.00) EPHX2
SCHEMBL27870160 0.75 EPHX2 (1.00) EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120315283-A1 METHODS OF PROMOTING TISSUE GROWTH AND TISSUE REGENERATION DANA-FARBER CANCER INSTITUTE, INC. (US) 2012-12-13 US disclosed
WO-2011097221-A2 METHODS OF PROMOTING TISSUE GROWTH AND TISSUE REGENERATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2011-08-11 WO disclosed