Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
| ▸ | CHKA | P35790 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409151 | 0.75 | CHRM5 (0.68) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8664726 | 0.75 | CHRM5 (1.00) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL189 | 0.75 | — | — | |
| Bromide SCHEMBL393564 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Water SCHEMBL19285054 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Bromide SCHEMBL1542160 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL2277093 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Phosphine SCHEMBL23270013 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL9013636 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A | |
| Bromide SCHEMBL393565 | 0.72 | CHRM5 (0.94) | CHRM5CHKAMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975088-B2 | Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors | INCYTE CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975088-B2 | Imidazo[2,1-f][1,2,4]triazine compounds as pi3k-y inhibitors | PIK3R5, PIK3CD, PIK3CA | CHRM5 4411/4885CHKA 362/4885MAPT 2945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.