Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 7/20 | 0.63 |
| ▸ | FGF1 | P05230 | 7/20 | 0.63 |
| ▸ | FGF2 | P09038 | 7/20 | 0.63 |
| ▸ | CDC25A | P30304 | 4/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | ST3GAL1 | Q11201 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23223301 | 1.00 | HPSE (0.63) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL21340577 | 0.96 | HPSE (0.65) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL24017722 | 0.93 | CDC25A (0.60) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL24017768 | 0.92 | HPSE (0.61) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL21340483 | 0.92 | HPSE (0.61) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL20004930 | 0.90 | CDC25A (0.61) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL21340268 | 0.88 | CDC25A (0.61) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL24017723 | 0.88 | CDC25A (0.61) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL23614817 | 0.81 | HPSE (0.61) | HPSEFGF1FGF2CDC25APOLA1 | |
| SCHEMBL19009194 | 0.80 | CDC25A (0.73) | HPSEFGF1CDC25APOLA1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515455-B1 | COMPOUNDS FOR TREATMENT OF LIPOPROTEIN METABOLISM DISORDERS | UNIV AARHUS (DK) | 2021-04-14 | — | — | EP | disclosed |