SCHEMBL23224912

SCHEMBL23224912

c1ccc(-c2ccccc2-c2ccccc2N(c2ccc(-c3cccc4ccccc34)cc2)c2cccc(-c3cccc4ccccc34)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.44
ACMSD Q8TDX5 1/20 0.44
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
TNF P01375 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
PPARG P37231 7/20 0.36
PPARA Q07869 7/20 0.36
CYP2C9 P11712 2/20 0.36
CYP2C19 P33261 2/20 0.36
PPARD Q03181 1/20 0.36
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23224910 0.99 MCL1 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL24816140 0.99 MCL1 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL24918435 0.99 MCL1 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL24815017 0.99 MCL1 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL23224907 0.97 MCL1 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL23238266 0.96 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL23238256 0.96 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL24919252 0.96 CA12 (0.43) MCL1ACMSDCA12CA1CA2
SCHEMBL24918947 0.96 MCL1 (0.45) MCL1ACMSDCA12CA1CA2
SCHEMBL23224913 0.96 MCL1 (0.43) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021070965-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2021-04-15 WO disclosed