SCHEMBL23225660

SCHEMBL23225660

CCOC(=O)C1(C2CCCCC2)CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.59
LMNA P02545 2/20 0.59
TSHR P16473 2/20 0.59
ABCB11 O95342 1/20 0.59
CYP1A2 P05177 1/20 0.59
CHRM2 P08172 1/20 0.59
CHRM4 P08173 1/20 0.59
CHRM5 P08912 1/20 0.59
CYP2D6 P10635 1/20 0.59
CHRM1 P11229 1/20 0.59
CYP2C9 P11712 1/20 0.59
CHRM3 P20309 1/20 0.59
DRD1 P21728 1/20 0.59
HRH2 P25021 1/20 0.59
HTR2A P28223 1/20 0.59
HTR2C P28335 1/20 0.59
HRH1 P35367 1/20 0.59
DRD3 P35462 1/20 0.59
SCN1A P35498 1/20 0.59
THPO P40225 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11858247 0.95 CYP3A4 (0.66) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL23225661 0.95 CYP3A4 (0.61) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL23225659 0.95 CYP3A4 (0.66) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL7733840 0.93 CYP3A4 (0.63) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL20103745 0.91 CYP3A4 (0.61) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL3637470 0.90 CYP3A4 (0.47) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL9013443 0.89 CYP3A4 (0.55) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL1311224 0.89 CYP3A4 (0.52) CYP3A4LMNATSHRABCB11CYP1A2
SCHEMBL18477543 0.87 CYP3A4 (0.54) CYP3A4LMNATSHRABCB11CYP1A2
Hydrochloric Acid SCHEMBL5729678 0.87 CYP3A4 (0.53) CYP3A4LMNATSHRABCB11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021072140-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. (US) 2021-04-15 WO disclosed