Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 3/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509733 | 0.81 | EGFR (0.55) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL18509959 | 0.67 | GPR17 (0.47) | EGFRTBXAS1APEX1KDM4EGAA | |
| SCHEMBL20120113 | 0.66 | KDM4E (0.73) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL19872722 | 0.65 | EGFR (0.56) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL18509938 | 0.64 | EGFR (0.54) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL20119993 | 0.64 | EGFR (0.54) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL20120170 | 0.64 | EGFR (0.54) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL18509719 | 0.64 | EGFR (0.54) | EGFRAPEX1MEN1KMT2AKDM4E | |
| SCHEMBL19872772 | 0.62 | APEX1 (0.56) | EGFRTBXAS1APEX1MEN1KMT2A | |
| SCHEMBL20935034 | 0.62 | EGFR (0.55) | EGFRTBXAS1APEX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287466-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH (US) | 2023-09-14 | — | — | US | disclosed |
| US-11591627-B2 | Modified bacteria for production of nitroaromatics | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210108237-A1 | WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-04-15 | — | — | US | disclosed |