Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.71 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16599480 | 0.85 | MCL1 (0.76) | MCL1SLC9A1MAPTDAOMEN1 | |
| SCHEMBL117186 | 0.83 | MCL1 (1.00) | MCL1SLC9A1MAPTDAOMEN1 | |
| SCHEMBL401039 | 0.83 | MCL1 (0.73) | MCL1SLC9A1MAPTDAOMEN1 | |
| SCHEMBL5748064 | 0.81 | MCL1 (0.71) | MCL1SLC9A1MAPTDAOMEN1 | |
| SCHEMBL2323444 | 0.81 | MCL1 (0.71) | MCL1SLC9A1MAPTDAOMEN1 | |
| Hydrochloric Acid SCHEMBL8600262 | 0.81 | MCL1 (0.96) | MCL1SLC9A1MAPTDAOMEN1 | |
| SCHEMBL4327040 | 0.81 | DAO (0.52) | MCL1SLC9A1MAPTDAO | |
| SCHEMBL10350688 | 0.80 | MCL1 (0.69) | MCL1SLC9A1MAPTDAOMEN1 | |
| Hydrochloric Acid SCHEMBL28264080 | 0.80 | MCL1 (0.69) | MCL1SLC9A1MAPTDAOMEN1 | |
| Potassium Ion SCHEMBL15876031 | 0.80 | MCL1 (0.69) | MCL1SLC9A1MAPTDAOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
| US-RE48175-E1 | Hydrophobically tagged small molecules as inducers of protein degradation | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-08-25 | — | — | US | disclosed |
| EP-1836174-B2 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2019-10-02 | — | — | EP | disclosed |
| EP-2534151-B1 | 8-METHYL-1-PHENYL-IMIDAZOL[1,5-A]PYRAZINE COMPOUNDS | MERCK SHARP & DOHME (NL) | 2018-11-14 | — | — | EP | disclosed |
| US-20180093990-A1 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-04-05 | — | — | US | disclosed |
| US-20180093990-A1 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-04-05 | — | — | US | disclosed |
| EP-2878601-B1 | AGENT FOR TREATING OR CONTROLLING RECURRENCE OF ACUTE MYELOGENOUS LEUKEMIA | RIKEN (JP) | 2018-03-28 | — | — | EP | disclosed |
| US-9758522-B2 | Hydrophobically tagged small molecules as inducers of protein degradation | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| EP-0539421-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-05 | — | — | EP | disclosed |
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |
| CN-1058215-A | Novel oxazolyl derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1992-01-29 | — | — | CN | disclosed |
| EP-0304223-A2 | Beta-carbolines as cholecy-stokinin and gastrin antagonist | MERCK & CO. INC. (US) | 1989-02-22 | — | — | EP | disclosed |
| US-4326065-A | PLASTICS, VARNISHES, POLYESTERS | EASTMAN KODAK COMPANY (US) | 1982-04-20 | — | — | US | disclosed |
| US-4251433-A | BENZOTRIAZOLE DERIVATIVES; FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
| US-4236013-A | ADDITIVES FOR POLYMERS | EASTMAN KODAK COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4137235-A | ULTRAVIOLET STABILIZERS IN POLYMERIC COMPOSITIONS | EASTMAN KODAK COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4116928-A | Heterocylic ester, ultraviolet stabilizers and their use in organic compositions | EASTMAN KODAK COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | MCL1 2380/4885SLC9A1 108/4885MAPT 510/4885 |
| US-20180093990-A1 | HYDROPHOBICALLY TAGGED SMALL MOLECULES AS INDUCERS OF PROTEIN DEGRADATION | MYC, TP53, MDM2 | MCL1 17/4885SLC9A1 4437/4885MAPT 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.