Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PANK3 | Q9H999 | 7/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12539812 | 0.88 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23215016 | 0.84 | CHRM1 (0.49) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23231394 | 0.84 | CHRM1 (0.55) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23215018 | 0.84 | CHRM1 (0.55) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL31464957 | 0.83 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL21522470 | 0.83 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL27424684 | 0.83 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL27424943 | 0.83 | RET (0.50) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL30859934 | 0.83 | CHRM1 (0.56) | CHRM1CHRM2CHRM4CHRM3KCNH2 | |
| SCHEMBL23215090 | 0.82 | CHRM1 (0.61) | CHRM1CHRM2CHRM4CHRM3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021071843-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | Pipeline Therapeutics, Inc. (US) | 2021-04-15 | — | — | WO | disclosed |