SCHEMBL2323353

SCHEMBL2323353

CC[C@@H](OS(=O)(=O)C(F)(F)F)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.32
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
PRSS3 P35030 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3069494 0.85 SMN1; SMN2 (0.35)
SCHEMBL2797629 0.85 SMN1; SMN2 (0.35)
SCHEMBL2327079 0.85 SMN1; SMN2 (0.35)
SCHEMBL15922161 0.80 HSD17B10 (0.35)
SCHEMBL2332745 0.80 CA1 (0.38) F2PRSS1PRSS2PRSS3
SCHEMBL21261493 0.80 CA1 (0.38) F2PRSS1PRSS2PRSS3
SCHEMBL2326461 0.80 HSD17B10 (0.35)
SCHEMBL15382587 0.80 CA1 (0.38) F2PRSS1PRSS2PRSS3
SCHEMBL7228766 0.77 AAK1 (0.33)
SCHEMBL2543881 0.77 AAK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1806339-B1 Process for the preparation of 2-oxo-1-pyrrolidine derivatives UCB PHARMA SA (BE) 2011-08-17 EP disclosed