Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211115 | 0.77 | — | — | |
| SCHEMBL19176286 | 0.73 | — | — | |
| SCHEMBL1109600 | 0.72 | — | — | |
| SCHEMBL1110107 | 0.67 | — | — | |
| SCHEMBL18085504 | 0.64 | TSHR (0.50) | LMNACYP2C9TSHR | |
| SCHEMBL61344 | 0.64 | — | — | |
| SCHEMBL3359573 | 0.64 | — | — | |
| SCHEMBL3359862 | 0.64 | — | — | |
| SCHEMBL12331443 | 0.62 | — | — | |
| SCHEMBL935302 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072269-A1 | TARGETED BIFUNCTIONAL DEGRADERS | YALE UNIVERSITY (US) | 2021-04-15 | — | — | WO | disclosed |