⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1257655 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3750224 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL11905554 | 0.97 | — | — | |
| SCHEMBL9748785 | 0.95 | — | — | |
| Lithium Ion SCHEMBL9748778 | 0.92 | — | — | |
| SCHEMBL3253094 | 0.90 | — | — | |
| SCHEMBL13836292 | 0.88 | — | — | |
| SCHEMBL16878643 | 0.83 | — | — | |
| SCHEMBL5422549 | 0.83 | — | — | |
| SCHEMBL767920 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12247064-B2 | Modified ligand-gated ion channels and methods of use | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-03-11 | — | — | US | claimed |
| WO-2025015092-A1 | NOVEL CAM-KINASE PROMOTER AND USES THEREOF FOR TREATING NERVOUS SYSTEM DISORDERS | KRIYA THERAPEUTICS, INC. (US) | 2025-01-16 | — | — | WO | claimed |
| CN-119120484-A | Modified ligand-gated ion channels and methods of use | 霍华休斯医学研究院 | 2024-12-13 | — | — | CN | claimed |
| US-20230323402-A1 | Targeted Gene Therapies for Pain and Other Neuro-Related Disorders | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2023-10-12 | — | — | US | claimed |
| US-11713470-B2 | Targeted gene therapies for pain and other neuro-related disorders | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2023-08-01 | — | — | US | claimed |
| CN-116288418-A | Preparation of carbon-based hydrophobic catalytic electrode material and application of carbon-based hydrophobic catalytic electrode material in carbon dioxide electrocatalysis | 国家能源集团新能源技术研究院有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-11124554-B2 | Modified ligand-gated ion channels and methods of use | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-09-21 | — | — | US | claimed |
| US-11084853-B2 | Modified ligand-gated ion channels and methods of use | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2021-08-10 | — | — | US | claimed |
| US-20210206831-A1 | MODIFIED LIGAND-GATED ION CHANNELS AND METHODS OF USE | HOWARD HUGHES MEDICAL INSTITUTE | 2021-07-08 | — | — | US | claimed |
| EP-3486245-B1 | 2-AMINO-N-(PIPERIDIN-1-YL-PYRIDIN-3-YL) PYRAZOLO[1,5ALPHA]PYRIMIDINE-3-CARBOXAMID AS INHIBITOR OF ATR KINASE | VERTEX PHARMA (US) | 2021-04-28 | — | — | EP | claimed |
| EP-1289987-B1 | 4-(2-PHENYLTHIAZOL-5-YL)-1,4-DIAZABICYCLO- 3.2.2]NONANE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SYNTHELABO (FR) | 2004-05-19 | — | — | EP | claimed |
| EP-1289986-B1 | 1,4-DIAZABICYCLO 3.2.2]NONANE-PHENYLISOXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SYNTHELABO (FR) | 2004-04-28 | — | — | EP | claimed |
| US-20040029884-A1 | 4-(2 phenylthiazol-5-yl)-1, 4-diazabicyclo-[3.2.2]nonane deirvatives, preparation and therapeutic use thereof | SANOFI (FR) | 2004-02-12 | — | — | US | claimed |
| EP-1254139-B1 | 4-HETEROARYL-1,4-DIAZABICYCLO 3.2.2]NONANE, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI SYNTHELABO (FR) | 2003-08-20 | — | — | EP | claimed |
| US-20030153574-A1 | 1,4-diazabicyclo[3.2.2]nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation and therapeutic use thereof | SANOFI (FR) | 2003-08-14 | — | — | US | claimed |
| US-20030119840-A1 | 4-Heteroparyl-1,4-diazabicyclo[3.2.2]nonane, preparation and therapeutic use thereof | SANOFI (FR) | 2003-06-26 | — | — | US | claimed |
| US-20030114461-A1 | 1,4-Diazabicyclo[3.2.2]nonane-phenylisoxazole derivatives, preparation and therapeutic use thereof | SANOFI (FR) | 2003-06-19 | — | — | US | claimed |
| EP-1289986-A1 | 1,4-DIAZABICYCLO 3.2.2]NONANE-PHENYLISOXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2003-03-12 | — | — | EP | claimed |
| WO-2001092259-A1 | 1,4-DIAZABICYCLO[3.2.2]NONANE-PHENYLISOXAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-SYNTHELABO (FR) | 2001-12-06 | — | — | WO | claimed |
| US-5185320-A | Antibiotics | GRUPPO LEPETIT S.P.A. (IT) | 1993-02-09 | — | — | US | claimed |