Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 14/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | CSF1R | P07333 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potrasertib SCHEMBL21373352 | 0.95 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 | |
| Potrasertib SCHEMBL27123597 | 0.95 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 | |
| Potrasertib SCHEMBL29506543 | 0.95 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 | |
| Potrasertib SCHEMBL23246139 | 0.95 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 | |
| Potrasertib SCHEMBL29859319 | 0.95 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 | |
| SCHEMBL27131603 | 0.92 | WEE1 (0.61) | WEE1KCNH2EGFRCSF1R | |
| SCHEMBL21373356 | 0.92 | WEE1 (0.61) | WEE1KCNH2EGFRCSF1R | |
| SCHEMBL29506494 | 0.92 | WEE1 (0.61) | WEE1KCNH2EGFRCSF1R | |
| SCHEMBL21373331 | 0.90 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 | |
| SCHEMBL29506471 | 0.90 | WEE1 (0.63) | WEE1KCNH2EGFRCSF1RJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118338905-A | Use of Wee1 kinase inhibitors in the treatment of cancer | 上海瑛派药业有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-117202908-A | Use of Wee1 kinase inhibitors in the treatment of cancer diseases | 上海瑛派药业有限公司 | 2023-12-08 | — | — | CN | claimed |
| WO-2023093840-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2023-06-01 | — | — | WO | claimed |
| WO-2022188802-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2022-09-15 | — | — | WO | claimed |
| CN-118338905-A | Use of Wee1 kinase inhibitors in the treatment of cancer | 上海瑛派药业有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-114502559-B | Dihydroimidazoles and pyrimido pyrimidinone compounds | 上海瑛派药业有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117202908-A | Use of Wee1 kinase inhibitors in the treatment of cancer diseases | 上海瑛派药业有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023093840-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2023-06-01 | — | — | WO | disclosed |
| WO-2022188802-A1 | USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2022-09-15 | — | — | WO | disclosed |
| CN-114502559-A | Dihydroimidazopyrimidopyrimidinones | 上海瑛派药业有限公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021073491-A1 | DIHYDROIMIDAZO PYRIMIDO PYRIMIDINONE COMPOUND | 上海瑛派药业有限公司 | 2021-04-22 | — | — | WO | disclosed |