Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.75 |
| ▸ | FABP4 | P15090 | 8/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 8/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | OGT | O15294 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530251 | 0.94 | CRBN (0.74) | CRBNBRPF1TP53IKBKBCHUK | |
| SCHEMBL1530434 | 0.89 | CRBN (0.77) | CRBNBRPF1TP53KDM4EALDH1A1 | |
| SCHEMBL11994036 | 0.88 | CRBN (0.79) | CRBNBRPF1TP53IKBKBCHUK | |
| SCHEMBL1530347 | 0.88 | CRBN (0.79) | CRBNBRPF1TP53OGTLMNA | |
| SCHEMBL1530499 | 0.87 | CRBN (0.80) | CRBNBRPF1TP53OGTLMNA | |
| SCHEMBL1530175 | 0.87 | CRBN (0.77) | CRBNBRPF1TP53ALDH1A1OGT | |
| SCHEMBL15943725 | 0.87 | CRBN (0.77) | CRBNFABP4FABP5BRPF1TP53 | |
| SCHEMBL1530732 | 0.87 | CRBN (0.77) | CRBNBRPF1TP53IKBKBCHUK | |
| SCHEMBL1530188 | 0.87 | CRBN (0.83) | CRBNFABP4FABP5BRPF1TP53 | |
| Dasabuvir SCHEMBL2367604 | 0.86 | CRBN (0.97) | CRBNBRPF1TP53OGTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203431-B1 | ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF | ABBOTT LAB (US) | 2011-08-10 | — | — | EP | claimed |