⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380318 | 1.00 | — | — | |
| SCHEMBL6379756 | 1.00 | — | — | |
| SCHEMBL7962562 | 1.00 | — | — | |
| SCHEMBL7975968 | 1.00 | — | — | |
| SCHEMBL7962299 | 1.00 | — | — | |
| SCHEMBL7064189 | 1.00 | — | — | |
| SCHEMBL1732883 | 0.80 | CHRM1 (0.48) | — | |
| SCHEMBL11458567 | 0.79 | — | — | |
| SCHEMBL11201004 | 0.77 | — | — | |
| SCHEMBL2286524 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854605-A | Method for synthesizing L-allo-isoleucine | 康化（上海）新药研发有限公司 | 2023-10-10 | — | — | CN | claimed |
| US-20240174632-A1 | INHIBITING HUMAN INTEGRIN (ALPHA-4) (BETA-7) | MORPHIC THERAPEUTIC, INC. (US) | 2024-05-30 | — | — | US | disclosed |
| CN-116854605-A | Method for synthesizing L-allo-isoleucine | 康化（上海）新药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-116854605-A | Method for synthesizing L-allo-isoleucine | 康化（上海）新药研发有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-115087444-A | Inhibition of human integrin alpha 4 β 7 | 莫菲克医疗股份有限公司 | 2022-09-20 | — | — | CN | disclosed |
| US-11370773-B1 | Inhibiting human integrin (alpha-4) (beta-7) | MORPHIC THERAPEUTIC, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| WO-2021076902-A1 | INHIBITING HUMAN INTEGRIN α 4 β 7 | MORPHIC THERAPEUTIC, INC. (US) | 2021-04-22 | — | — | WO | disclosed |
| WO-2021076890-A1 | INHIBITING HUMAN INTEGRIN α4β7 | MORPHIC THERAPEUTIC, INC. (US) | 2021-04-22 | — | — | WO | disclosed |