Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329561 | 0.93 | ADORA2A (0.73) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2323998 | 0.93 | ADORA2A (0.79) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2319984 | 0.84 | ADORA2A (0.82) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2322065 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2322516 | 0.81 | ADORA2A (0.76) | ADORA2AADORA1ADORA2B | |
| SCHEMBL17667882 | 0.81 | ADORA2A (0.52) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2321400 | 0.80 | ADORA2A (0.81) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2323349 | 0.79 | ADORA2A (0.81) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2323578 | 0.79 | ADORA2A (0.75) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2327585 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531492-A1 | 1,2,4-TRIAZINE-4-AMINE DERIVATIVES | Heptares Therapeutics Limited (GB) | 2012-12-12 | — | — | EP | claimed |
| WO-2011095625-A1 | 1,2,4-TRIAZINE-4-AMINE DERIVATIVES | HEPTARES THERAPEUTICS LIMITED (GB) | 2011-08-11 | — | — | WO | claimed |