Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512906 | 0.79 | MCHR1 (0.50) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL4503035 | 0.73 | MCHR1 (0.55) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL2323297 | 0.72 | MCHR1 (0.53) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL2326974 | 0.70 | MCHR1 (0.49) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL4519018 | 0.70 | MCHR1 (0.49) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL2321880 | 0.69 | MCHR1 (0.62) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL5230226 | 0.68 | MCHR1 (0.61) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL13933782 | 0.68 | MCHR1 (0.53) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL2324871 | 0.68 | MCHR1 (0.53) | MCHR1CHRM1HTR2ACYP2D6 | |
| SCHEMBL5220840 | 0.68 | MCHR1 (0.57) | MCHR1CHRM1HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2357173-A1 | New alkyne compounds with MCH-antagonistic activity and medicaments containing them | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2011-08-17 | — | — | EP | disclosed |