Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.68 |
| ▸ | ALPL | P05186 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22732150 | 0.96 | PPARG (0.79) | PPARGCYP3A4ALPL | |
| SCHEMBL24318052 | 0.94 | PPARG (0.75) | PPARGCYP3A4ALPL | |
| SCHEMBL16302709 | 0.93 | PPARG (0.64) | PPARGCYP3A4ALPL | |
| SCHEMBL23258335 | 0.93 | PPARG (0.77) | PPARGCYP3A4ALPL | |
| SCHEMBL23258935 | 0.92 | PPARG (0.67) | PPARGCYP3A4ALPL | |
| SCHEMBL10060331 | 0.89 | PPARG (0.82) | PPARGCYP3A4ALPL | |
| SCHEMBL24268600 | 0.89 | PPARG (0.87) | PPARGCYP3A4 | |
| SCHEMBL7996313 | 0.89 | PPARG (0.83) | PPARGCYP3A4ALPL | |
| SCHEMBL24268582 | 0.87 | PPARG (0.72) | PPARGCYP3A4 | |
| SCHEMBL22517721 | 0.86 | PPARG (0.71) | PPARGCYP3A4ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076616-A1 | COMPOSITIONS AND METHODS TO TREAT NON-ALCOHOLIC FATTY LIVER DISEASES (NAFLD) | Coherus Biosciences, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |