⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997891 | 0.64 | — | — | |
| SCHEMBL171853 | 0.64 | HDAC8 (0.47) | — | |
| SCHEMBL6017584 | 0.63 | — | — | |
| SCHEMBL28383937 | 0.61 | HDAC8 (0.44) | — | |
| SCHEMBL17144230 | 0.61 | HDAC8 (0.44) | — | |
| SCHEMBL29810143 | 0.61 | HDAC8 (0.44) | — | |
| Hydrochloric Acid SCHEMBL6535289 | 0.61 | HDAC8 (0.44) | — | |
| Hydrochloric Acid SCHEMBL29713633 | 0.61 | HDAC8 (0.44) | — | |
| Hydrochloric Acid SCHEMBL6534749 | 0.61 | HDAC8 (0.44) | — | |
| SCHEMBL4270187 | 0.61 | HDAC8 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2259 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018021-B2 | Thiophene derivatives for the treatment of disorders caused by IgE | UCB Biopharma SRL (BE) | 2024-06-25 | — | — | US | claimed |
| US-20240092773-A1 | DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES | UCB Biopharma SRL (BE) | 2024-03-21 | — | — | US | claimed |
| CN-116751200-A | Tricyclic compounds containing substituted pyridones and methods of using the same | 爱彼特生物制药公司 | 2023-09-15 | — | — | CN | claimed |
| CN-110114071-B | Tricyclic compounds containing substituted pyridones and methods of using the same | 爱彼特生物制药公司 | 2023-07-04 | — | — | CN | claimed |
| US-20230125481-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2023-04-27 | — | — | US | claimed |
| US-20230129907-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC INTERNATIONAL GMBH (DE) | 2023-04-27 | — | — | US | claimed |
| EP-4117780-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | Evotec International GmbH (DE) | 2023-01-18 | — | — | EP | claimed |
| EP-4096665-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | Evotec International GmbH (DE) | 2022-12-07 | — | — | EP | claimed |
| WO-2022240213-A1 | NOVEL BENZOTHIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF FOR PREVENTION OR TREATMENT OF LIVER DISEASE | 에이치케이이노엔 주식회사 | 2022-11-17 | — | — | WO | claimed |
| US-20220227747-A1 | MODULATORS OF THE INTEGRATED STRESS RESPONSE PATHWAY | EVOTEC (UK) LIMITED (GB) | 2022-07-21 | — | — | US | claimed |
| US-4873224-A | Avermectin derivatives | MERCK & CO., INC. (US) | 1989-10-10 | — | — | US | claimed |
| US-4841049-A | FOR CELLULOSIC FIBERS; BRIGHT BLUE COLORS; WET- AND LIGHTFAST | CIBA-GEIGY CORPORATION (US) | 1989-06-20 | — | — | US | claimed |
| US-4797482-A | Process for the preparation of oxazinobenzothiazine 6,6-dioxide derivatives | PROVESAN S.A. (CH) | 1989-01-10 | — | — | US | claimed |
| EP-0273409-A1 | Nitrohaloalkoxybenzenes, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-06 | — | — | EP | claimed |
| EP-0242289-A1 | Process for the preparation of oxazinobenzothiazine 6,6-dioxide derivatives | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-10-21 | — | — | EP | claimed |
| US-4680384-A | PYRIMIDINE DYES | CIBA-GEIGY CORPORATION (US) | 1987-07-14 | — | — | US | claimed |
| US-4447357-A | Fibre-reactive azo dyestuffs containing a halotriazinyl radical and a non-reactive triazinyl radical | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | claimed |
| US-4436921-A | CARCINOSTATIC ACTIVITY | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | claimed |
| US-4132436-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1979-01-02 | — | — | US | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |