SCHEMBL2326246

SCHEMBL2326246

CCC[C@@H](CN[C@@H](CC)C(=O)OC)CC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TAS1R3 Q7RTX0 3/20 0.33
TAS1R1 Q7RTX1 3/20 0.33
POLB P06746 1/20 0.33
ZDHHC7 Q9NXF8 1/20 0.33
BIRC2 Q13490 4/20 0.32
KMT2A Q03164 1/20 0.31
GPR84 Q9NQS5 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2326252 1.00 CA1 (0.38) CA1CA2TAS1R3TAS1R1POLB
SCHEMBL2330257 0.88 CA1 (0.38) CA1CA2TAS1R3TAS1R1POLB
SCHEMBL2330255 0.88 CA1 (0.38) CA1CA2TAS1R3TAS1R1POLB
SCHEMBL2324298 0.85 CHRM1 (0.36) CA2POLBGPR84
SCHEMBL2324304 0.85 CHRM1 (0.36) CA2POLBGPR84
SCHEMBL2330262 0.85 MGAM (0.36) CA1CA2TAS1R3TAS1R1POLB
SCHEMBL2330264 0.85 MGAM (0.36) CA1CA2TAS1R3TAS1R1POLB
SCHEMBL23311196 0.83 CA1 (0.33) CA1CA2GPR84
SCHEMBL21602737 0.83 CA1 (0.33) CA1CA2GPR84
SCHEMBL21602746 0.83 CA1 (0.33) CA1CA2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338621-B2 Process for the preparation of 2-oxo-1-pyrrolidine derivatives UCB S.A. (BE) 2012-12-25 US disclosed
EP-1806339-B1 Process for the preparation of 2-oxo-1-pyrrolidine derivatives UCB PHARMA SA (BE) 2011-08-17 EP disclosed
US-20080009638-A1 PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES UCB S.A. (BE) 2008-01-10 US disclosed
EP-1806339-A1 Process for the preparation of 2-oxo-1-pyrrolidine derivatives UCB, S.A. (BE) 2007-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009638-A1 PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES CYP2F1, CYP3A5, SULT1E1 CA1 2079/4885CA2 1508/4885TAS1R3 1656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.