Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263317 | 0.85 | CTPS1 (0.33) | DYRK1ACTPS1ABL1RPS6KB1CSNK1D | |
| SCHEMBL23263316 | 0.83 | CTPS1 (0.32) | DYRK1ACTPS1ABL1RPS6KB1CSNK1D | |
| SCHEMBL23263935 | 0.81 | CHRNB4 (0.40) | DYRK1ACTPS1ABL1RPS6KB1CSNK1D | |
| SCHEMBL29890449 | 0.79 | CYP3A4 (0.41) | DYRK1APARP10PARP11PTPN5 | |
| SCHEMBL23249843 | 0.79 | CYP3A4 (0.41) | DYRK1APARP10PARP11PTPN5 | |
| SCHEMBL23258467 | 0.78 | SCN5A (0.40) | SCN5ASCN9ASCN10A | |
| SCHEMBL27018507 | 0.76 | CTSA (0.37) | DYRK1AABL1PARP10PARP11LGMN | |
| SCHEMBL23258801 | 0.73 | SCN5A (0.40) | SCN5ASCN9ASCN10A | |
| SCHEMBL23263161 | 0.72 | PARP10 (0.35) | DYRK1AABL1PARP10PARP11 | |
| SCHEMBL23263129 | 0.72 | BACE1 (0.39) | DYRK1ACTPS1ABL1RPS6KB1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076945-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |