Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 16/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.48 |
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31595518 | 1.00 | PTK2 (0.53) | PTK2CRBNBTKAR | |
| SCHEMBL23267313 | 0.94 | CRBN (0.49) | PTK2CRBNBTKAR | |
| SCHEMBL31595211 | 0.94 | CRBN (0.49) | PTK2CRBNBTKAR | |
| SCHEMBL23268167 | 0.91 | PTK2 (0.49) | PTK2CRBNBTKAR | |
| SCHEMBL23249916 | 0.91 | BCL6 (0.57) | PTK2CRBNBTKAR | |
| SCHEMBL29874152 | 0.91 | BCL6 (0.57) | PTK2CRBNBTKAR | |
| SCHEMBL23249960 | 0.91 | BCL6 (0.57) | PTK2CRBNBTKAR | |
| SCHEMBL29874253 | 0.91 | BCL6 (0.57) | PTK2CRBNBTKAR | |
| SCHEMBL23267394 | 0.90 | PTK2 (0.50) | PTK2CRBNBTKAR | |
| SCHEMBL31595205 | 0.90 | PTK2 (0.50) | PTK2CRBNBTKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |