Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 18/20 | 0.64 |
| ▸ | MELK | Q14680 | 1/20 | 0.64 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.63 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23267217 | 0.94 | BCL6 (0.62) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267749 | 0.94 | BCL6 (0.64) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267218 | 0.94 | BCL6 (0.61) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23266772 | 0.93 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267047 | 0.92 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL24717369 | 0.92 | BCL6 (0.68) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267051 | 0.92 | BCL6 (0.66) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267251 | 0.92 | BCL6 (0.66) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL29333237 | 0.91 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23266770 | 0.91 | BCL6 (0.64) | BCL6MELKNCOR2CHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |