Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 17/20 | 0.61 |
| ▸ | MELK | Q14680 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.53 |
| ▸ | WEE1 | P30291 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23266777 | 0.94 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267215 | 0.92 | BCL6 (0.61) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL24718194 | 0.92 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267757 | 0.91 | BCL6 (0.62) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23266769 | 0.91 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267218 | 0.91 | BCL6 (0.61) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL24717334 | 0.90 | BCL6 (0.67) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL29333174 | 0.90 | BCL6 (0.62) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL20284552 | 0.89 | BCL6 (0.71) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267051 | 0.88 | BCL6 (0.66) | BCL6MELKNCOR2CHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |