Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 4/20 | 0.37 |
| ▸ | BCOR | Q6W2J9 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 4/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249944 | 0.87 | BCL6 (0.39) | BCL6BCORGABRG2GABRB3GABRA5 | |
| SCHEMBL29874089 | 0.87 | BCL6 (0.39) | BCL6BCORGABRG2GABRB3GABRA5 | |
| SCHEMBL29874016 | 0.83 | BCL6 (0.40) | BCL6BCORGABRG2GABRB3GABRA5 | |
| SCHEMBL23249920 | 0.83 | BCL6 (0.40) | BCL6BCORGABRG2GABRB3GABRA5 | |
| SCHEMBL23249934 | 0.81 | CRBN (0.38) | BCL6BCOR | |
| SCHEMBL23249931 | 0.81 | CRBN (0.38) | BCL6BCOR | |
| SCHEMBL23249988 | 0.76 | CRBN (0.37) | BCL6BCOR | |
| SCHEMBL31595469 | 0.73 | CRBN (0.50) | ALK | |
| SCHEMBL31595459 | 0.68 | MAPT (0.41) | BCL6BCORMAPT | |
| SCHEMBL22955126 | 0.60 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |