Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10204847 | 0.98 | TAAR1 (0.53) | TAAR1IDO1HCAR2HRH3DAO | |
| SCHEMBL14972583 | 0.86 | TAAR1 (0.52) | TAAR1IDO1HCAR2HRH3DAO | |
| SCHEMBL10378465 | 0.86 | TAAR1 (0.52) | TAAR1IDO1HCAR2HRH3DAO | |
| SCHEMBL10204846 | 0.85 | TAAR1 (0.55) | TAAR1IDO1HCAR2HRH3DAO | |
| SCHEMBL10204837 | 0.81 | IDO1 (0.58) | TAAR1IDO1HCAR2ALDH1A1CYP2D6 | |
| SCHEMBL16353983 | 0.81 | TAAR1 (0.47) | TAAR1IDO1HCAR2HRH3DAO | |
| SCHEMBL6229666 | 0.79 | CA1 (0.42) | TAAR1IDO1HRH3ALDH1A1 | |
| SCHEMBL168757 | 0.78 | TAAR1 (0.65) | TAAR1IDO1HRH3DAOALDH1A1 | |
| SCHEMBL29462896 | 0.78 | TAAR1 (0.65) | TAAR1IDO1HRH3DAOALDH1A1 | |
| SCHEMBL2608904 | 0.77 | TAAR1 (0.50) | TAAR1IDO1HCAR2HRH3DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |