Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12347298 | 0.91 | SMN1; SMN2 (0.45) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL23603456 | 0.90 | HRH3 (0.37) | NCF1CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL12049732 | 0.89 | HRH3 (0.42) | NCF1CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL13162611 | 0.87 | HRH3 (0.41) | NCF1CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL1934995 | 0.85 | CHRM4 (0.34) | NCF1CHRM1CHRM4CHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL1935604 | 0.83 | CHRM4 (0.33) | CHRM1CHRM4CHRM5CHRM3MAPK1 | |
| SCHEMBL29303972 | 0.83 | CHRM3 (0.33) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL29304327 | 0.83 | CHRM3 (0.33) | CHRM1CHRM4CHRM5CHRM3CHRM2 | |
| SCHEMBL22597886 | 0.82 | HRH3 (0.38) | NCF1CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL1936071 | 0.80 | CHRM3 (0.44) | CHRM1CHRM4CHRM5CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |