Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TKT | P29401 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23269422 | 0.87 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1KDM4ELMNAKMT2A | |
| SCHEMBL29464842 | 0.82 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1KDM4ELMNATKT | |
| SCHEMBL23269465 | 0.82 | HSP90AA1 (0.37) | HSP90AA1HSP90AB1KDM4ELMNATKT | |
| SCHEMBL29076623 | 0.75 | ADORA2A (0.33) | HSP90AA1HSP90AB1KDM4EKMT2AMEN1 | |
| SCHEMBL11985857 | 0.74 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1KDM4ELMNAKMT2A | |
| SCHEMBL18018164 | 0.72 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1KDM4ELMNAKMT2A | |
| SCHEMBL14967196 | 0.71 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1KDM4ELMNATKT | |
| SCHEMBL21603492 | 0.71 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1KDM4ELMNAKMT2A | |
| SCHEMBL25880579 | 0.71 | KLKB1 (0.38) | KDM4ELMNAKMT2AHSD17B10CYP3A4 | |
| SCHEMBL31214472 | 0.70 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1KDM4ELMNATKT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230000847-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | DRAIG THERAPEUTICS LTD (GB) | 2023-01-05 | — | — | US | disclosed |
| US-11298345-B2 | Compounds that modulates AMPA receptor function | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-04-12 | — | — | US | disclosed |
| US-20210113539-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | DRAIG THERAPEUTICS LTD (GB) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230000847-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | GRIN1, GRM1, GRIN2A | HSP90AA1 4014/4885HSP90AB1 3893/4885KDM4E 3845/4885 |
| US-20210113539-A1 | COMPOUNDS THAT MODULATES AMPA RECEPTOR FUNCTION | GRIN1, GRM1, GRIN2A | HSP90AA1 4014/4885HSP90AB1 3893/4885KDM4E 3845/4885 |
| US-11298345-B2 | Compounds that modulates AMPA receptor function | GRIN1, GRM1, GRIN2A | HSP90AA1 4014/4885HSP90AB1 3893/4885KDM4E 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.