Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21602746 | 1.00 | CA1 (0.33) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL23311196 | 1.00 | CA1 (0.33) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL20767989 | 1.00 | CA1 (0.33) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL21602737 | 1.00 | CA1 (0.33) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| SCHEMBL2327334 | 1.00 | CA1 (0.33) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| Hydrochloric Acid SCHEMBL6778482 | 0.98 | CA1 (0.33) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| Oxalic Acid SCHEMBL23270124 | 0.97 | CA1 (0.32) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| Oxalic Acid SCHEMBL23270122 | 0.97 | CA1 (0.32) | CA1CA2CACNA2D1ADRA1ACACNB3 | |
| Maleic Acid SCHEMBL23270119 | 0.93 | HCAR2 (0.32) | — | |
| Maleic Acid SCHEMBL23270121 | 0.93 | HCAR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615744-B | Buvalracetam intermediate and preparation method thereof | 上海朴颐化学科技有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-110615744-A | Buvalracetam intermediate and preparation method thereof | 上海朴颐化学科技有限公司 | 2019-12-27 | — | — | CN | claimed |
| EP-1265862-B1 | 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB SA (BE) | 2005-09-21 | — | — | EP | claimed |
| US-12365649-B2 | Process for the preparation of brivaracetam | ALIVUS LIFE SCIENCES LIMITED (IN) | 2025-07-22 | — | — | US | disclosed |
| CN-112020498-B | Buvalracetam intermediate, preparation method thereof and preparation method of Buvalracetam | 上海朴颐化学科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20240010618-A1 | PROCESS FOR THE PREPARATION OF BRIVARACETAM | ALIVUS LIFE SCIENCES LIMITED (IN) | 2024-01-11 | — | — | US | disclosed |
| CN-110615744-B | Buvalracetam intermediate and preparation method thereof | 上海朴颐化学科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| US-11518741-B2 | Brivaracetam intermediate, preparation method therefor, and preparation method for brivaracetam | SHANGHAI PUYI CHEMICAL CO., LTD. (CN) | 2022-12-06 | — | — | US | disclosed |
| US-11518741-B2 | Brivaracetam intermediate, preparation method therefor, and preparation method for brivaracetam | SHANGHAI PUYI CHEMICAL CO., LTD. (CN) | 2022-12-06 | — | — | US | disclosed |
| US-20210253523-A1 | BRIVARACETAM INTERMEDIATE, PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR BRIVARACETAM | SHANGHAI PUYI CHEMICAL CO., LTD. (CN) | 2021-08-19 | — | — | US | disclosed |
| US-20210253523-A1 | BRIVARACETAM INTERMEDIATE, PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR BRIVARACETAM | SHANGHAI PUYI CHEMICAL CO., LTD. (CN) | 2021-08-19 | — | — | US | disclosed |
| EP-3812377-A1 | BRIVARACETAM INTERMEDIATE, PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR BRIVARACETAM | Shanghai Puyi Chemical Co., Ltd. (CN) | 2021-04-28 | — | — | EP | disclosed |
| CN-111187175-A | Method for preparing intermediate of brivaracetam by hydrogenation of microchannel reactor | 上海朴颐化学科技有限公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-110615744-A | Buvalracetam intermediate and preparation method thereof | 上海朴颐化学科技有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-110615744-A | Buvalracetam intermediate and preparation method thereof | 上海朴颐化学科技有限公司 | 2019-12-27 | — | — | CN | disclosed |
| WO-2019242192-A1 | BRIVARACETAM INTERMEDIATE, PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR BRIVARACETAM | 上海朴颐化学科技有限公司 | 2019-12-26 | — | — | WO | disclosed |
| US-8338621-B2 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB S.A. (BE) | 2012-12-25 | — | — | US | disclosed |
| EP-1806339-B1 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB PHARMA SA (BE) | 2011-08-17 | — | — | EP | disclosed |
| US-20080009638-A1 | PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES | UCB S.A. (BE) | 2008-01-10 | — | — | US | disclosed |
| EP-1806339-A1 | Process for the preparation of 2-oxo-1-pyrrolidine derivatives | UCB, S.A. (BE) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009638-A1 | PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES | CYP2F1, CYP3A5, SULT1E1 | CA1 2079/4885CA2 1508/4885CACNA2D1 352/4885 |
| US-11518741-B2 | Brivaracetam intermediate, preparation method therefor, and preparation method for brivaracetam | CYP51A1, FAR1, POR | CA1 3969/4885CA2 1455/4885CACNA2D1 319/4885 |
| US-20210253523-A1 | BRIVARACETAM INTERMEDIATE, PREPARATION METHOD THEREFOR, AND PREPARATION METHOD FOR BRIVARACETAM | CYP51A1, FAR1, POR | CA1 3969/4885CA2 1455/4885CACNA2D1 319/4885 |
| US-12365649-B2 | Process for the preparation of brivaracetam | CYP2C19, CYP2B6, POR | CA1 2579/4885CA2 453/4885CACNA2D1 1281/4885 |
| US-20240010618-A1 | PROCESS FOR THE PREPARATION OF BRIVARACETAM | CYP2C19, CYP2B6, POR | CA1 2579/4885CA2 453/4885CACNA2D1 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.