Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 20/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23289661 | 0.95 | TLR8 (0.39) | TLR8TLR7 | |
| SCHEMBL23273943 | 0.94 | TLR8 (0.40) | TLR8TLR7 | |
| SCHEMBL23289659 | 0.92 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL23289576 | 0.90 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL23289663 | 0.89 | TLR8 (0.39) | TLR8TLR7 | |
| SCHEMBL23274143 | 0.89 | TLR8 (0.36) | TLR8TLR7 | |
| SCHEMBL23274098 | 0.88 | TLR8 (0.39) | TLR8TLR7 | |
| SCHEMBL23289361 | 0.87 | TLR8 (0.52) | TLR8TLR7 | |
| SCHEMBL23274206 | 0.86 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL23273945 | 0.86 | TLR8 (0.37) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081407-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| WO-2021081402-A1 | MACROMOLECULE-SUPPORTED THIENOAZEPINE COMPOUNDS, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-04-29 | — | — | WO | disclosed |
| WO-2021081407-A1 | THIENOAZEPINE IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-04-29 | — | — | WO | disclosed |