SCHEMBL232756

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL236303	0.87	TAAR1 (0.49)	TAAR1LTA4HPLA2G2AFFAR1F2
	SCHEMBL232484	0.86	TAAR1 (0.56)	TAAR1LTA4HPLA2G2AESR1CYP19A1
	SCHEMBL233812	0.85	TAAR1 (0.50)	TAAR1LTA4HPLA2G2AFFAR1
	SCHEMBL234577	0.85	TAAR1 (0.50)	TAAR1LTA4HPLA2G2A
	Hydrochloric Acid SCHEMBL611664	0.84	TAAR1 (0.49)	TAAR1LTA4HPLA2G2A
	SCHEMBL234437	0.82	TAAR1 (0.47)	TAAR1LTA4HPLA2G2AFFAR1
	SCHEMBL15912130	0.82	HTR1B (0.48)	TAAR1LTA4HPLA2G2AKCNA3F2
	SCHEMBL236413	0.82	TAAR1 (0.51)	TAAR1LTA4HPLA2G2AFFAR1
	SCHEMBL236505	0.82	CYP2A6 (0.50)	TAAR1LTA4HPLA2G2A
	SCHEMBL2754666	0.82	TAAR1 (0.46)	TAAR1LTA4HPLA2G2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.