SCHEMBL23275696

SCHEMBL23275696

Cn1cc(Nc2nccc(-c3ccc(C(=O)O)cc3)n2)cn1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CAMK2D Q13557 6/20 0.66
▸ MAPK8 P45983 3/20 0.58
▸ PIK3CG P48736 2/20 0.58
▸ CAMKK2 Q96RR4 2/20 0.58
▸ GSK3B P49841 2/20 0.58
▸ JAK2 O60674 3/20 0.55
▸ JAK3 P52333 3/20 0.55
▸ JAK1 P23458 2/20 0.55
▸ TYK2 P29597 1/20 0.55
▸ STAT3 P40763 1/20 0.55
▸ CHEK1 O14757 1/20 0.53
▸ MAPK10 P53779 1/20 0.51
▸ CDK4 P11802 1/20 0.51
▸ CDK2 P24941 1/20 0.51
▸ BTK Q06187 5/20 0.51
▸ ABL1 P00519 1/20 0.50
▸ BCR P11274 1/20 0.50
▸ PRKCA P17252 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28353387 0.89 ABL1 (0.53) CAMK2DJAK2JAK3JAK1TYK2
SCHEMBL23275717 0.87 JAK2 (0.54) CAMK2DJAK2JAK3JAK1TYK2
SCHEMBL23275856 0.86 BTK (0.59) CAMKK2JAK2JAK3JAK1TYK2
SCHEMBL23275768 0.85 CDK2 (0.57) CAMK2DJAK2JAK3JAK1TYK2
SCHEMBL22115096 0.84 MAP3K14 (0.55) CAMK2DMAPK8PIK3CGCAMKK2GSK3B
SCHEMBL23275725 0.84 JAK2 (0.55) JAK2JAK3JAK1TYK2STAT3
SCHEMBL29901235 0.84 CDK4 (0.49) CAMK2DGSK3BJAK2JAK3JAK1
SCHEMBL23275907 0.84 CDK4 (0.49) CAMK2DGSK3BJAK2JAK3JAK1
SCHEMBL23275663 0.83 JAK2 (0.68) CAMK2DMAPK8JAK2JAK3JAK1
SCHEMBL23275741 0.83 JAK2 (0.59) JAK2JAK3JAK1TYK2STAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240174648-A1 Small Molecule Compound TECHNODERMA MEDICINES INC. (CN) 2024-05-30 — — US disclosed
EP-4050009-A1 SMALL MOLECULE COMPOUND Technoderma Medicines Pte Ltd (CN) 2022-08-31 — — EP disclosed
WO-2021078023-A1 SMALL MOLECULE COMPOUND 嘉兴特科罗生物科技有限公司 2021-04-29 — — WO disclosed
CN-110627775-A Small molecule compound 嘉兴特科罗生物科技有限公司 2019-12-31 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174648-A1 Small Molecule Compound JAK1, JAK2, TYK2 CAMK2D 439/4885MAPK8 358/4885PIK3CG 1114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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