SCHEMBL23276709

SCHEMBL23276709

N#CC=C1CCN(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 5/20 0.60
CYP1A2 P05177 3/20 0.60
CYP3A4 P08684 2/20 0.60
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.54
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
CYP2C19 P33261 1/20 0.52
ALDH1A1 P00352 2/20 0.51
ALOX15 P16050 2/20 0.51
HSD17B10 Q99714 2/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
HDAC2 Q92769 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19990247 0.86 MEN1 (0.51) GRM5CYP1A2CYP3A4MEN1KMT2A
SCHEMBL7311393 0.82 MEN1 (0.59) GRM5CYP1A2CYP3A4MEN1KMT2A
SCHEMBL9218512 0.82 MEN1 (0.59) GRM5CYP1A2CYP3A4MEN1KMT2A
SCHEMBL25878470 0.81 MEN1 (0.47) GRM5CYP1A2CYP3A4MEN1KMT2A
SCHEMBL9572627 0.80 MEN1 (0.57) GRM5CYP1A2CYP3A4MEN1KMT2A
SCHEMBL1700533 0.80 MEN1 (0.57) GRM5CYP1A2CYP3A4MEN1KMT2A
SCHEMBL4814264 0.80 MEN1 (0.76) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL379160 0.80 MEN1 (0.76) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL3970912 0.80 MEN1 (0.76) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL7393652 0.80 MEN1 (0.76) MEN1KMT2ANPSR1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021078021-A1 SMALL MOLECULAR COMPOUND 嘉兴特科罗生物科技有限公司 2021-04-29 WO disclosed