Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 19/20 | 0.57 |
| ▸ | JAK1 | P23458 | 19/20 | 0.57 |
| ▸ | TYK2 | P29597 | 19/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | PRKCB | P05771 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.53 |
| ▸ | PRKCH | P24723 | 1/20 | 0.53 |
| ▸ | PRKCI | P41743 | 1/20 | 0.53 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.53 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.53 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23277023 | 1.00 | JAK2 (0.57) | JAK2JAK1TYK2PRKD3PRKCG | |
| SCHEMBL23276886 | 1.00 | JAK2 (0.57) | JAK2JAK1TYK2PRKD3PRKCG | |
| SCHEMBL23276747 | 0.87 | JAK2 (0.58) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23276919 | 0.87 | JAK2 (0.58) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23276692 | 0.87 | JAK2 (0.58) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23276888 | 0.81 | JAK2 (0.57) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23299620 | 0.78 | TYK2 (0.59) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL24172505 | 0.76 | JAK2 (0.66) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL24172672 | 0.76 | JAK2 (0.66) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL22621338 | 0.76 | JAK2 (0.66) | JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |