Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.86 |
| ▸ | MAP4K1 | Q92918 | 19/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442753 | 0.93 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL17442841 | 0.83 | KLKB1 (0.76) | KLKB1MAP4K1 | |
| SCHEMBL17442709 | 0.80 | KLKB1 (0.78) | KLKB1MAP4K1 | |
| SCHEMBL17442755 | 0.80 | KLKB1 (0.72) | KLKB1MAP4K1 | |
| SCHEMBL18369647 | 0.80 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL18416809 | 0.79 | KLKB1 (0.82) | KLKB1MAP4K1 | |
| SCHEMBL17442746 | 0.78 | KLKB1 (0.71) | KLKB1MAP4K1 | |
| SCHEMBL17442512 | 0.78 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL16881340 | 0.78 | KLKB1 (0.82) | KLKB1MAP4K1 | |
| SCHEMBL17920386 | 0.78 | KLKB1 (0.79) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-B1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS INC (US) | 2021-04-28 | — | — | EP | disclosed |