Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.61 |
| ▸ | MAP4K1 | Q92918 | 9/20 | 0.61 |
| ▸ | KLK1 | P06870 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23279798 | 0.94 | KLKB1 (0.62) | KLKB1MAP4K1KLK1 | |
| SCHEMBL23279765 | 0.88 | KLKB1 (0.61) | KLKB1MAP4K1KLK1 | |
| SCHEMBL16881538 | 0.88 | KLKB1 (0.62) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17442729 | 0.87 | KLKB1 (0.70) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17442849 | 0.86 | KLKB1 (0.64) | KLKB1MAP4K1KLK1 | |
| SCHEMBL16880961 | 0.85 | KLKB1 (0.80) | KLKB1MAP4K1KLK1 | |
| SCHEMBL16880457 | 0.85 | KLKB1 (0.72) | KLKB1MAP4K1KLK1 | |
| SCHEMBL23279769 | 0.85 | KLKB1 (0.64) | KLKB1MAP4K1KLK1 | |
| SCHEMBL23279806 | 0.84 | KLKB1 (0.62) | KLKB1MAP4K1KLK1 | |
| SCHEMBL23279718 | 0.81 | KLKB1 (0.56) | KLKB1MAP4K1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-B1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS INC (US) | 2021-04-28 | — | — | EP | disclosed |