Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.56 |
| ▸ | MAP4K1 | Q92918 | 15/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17442609 | 0.83 | KLKB1 (0.66) | KLKB1MAP4K1 | |
| SCHEMBL17442586 | 0.81 | KLKB1 (0.68) | KLKB1MAP4K1 | |
| SCHEMBL19354910 | 0.78 | KLKB1 (0.62) | KLKB1MAP4K1 | |
| SCHEMBL17442588 | 0.72 | KLKB1 (0.64) | KLKB1MAP4K1 | |
| SCHEMBL17442642 | 0.72 | KLKB1 (1.00) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17442566 | 0.71 | KLKB1 (0.52) | KLKB1MAP4K1 | |
| SCHEMBL17442610 | 0.70 | KLKB1 (1.00) | KLKB1MAP4K1 | |
| SCHEMBL18369955 | 0.70 | KLKB1 (0.84) | KLKB1MAP4K1KLK1 | |
| SCHEMBL16891561 | 0.70 | KLKB1 (0.53) | KLKB1MAP4K1 | |
| SCHEMBL17920376 | 0.70 | KLKB1 (0.50) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169325-B1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS INC (US) | 2021-04-28 | — | — | EP | disclosed |