Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18376955 | 1.00 | IDH1 (1.00) | IDH1 | |
| SCHEMBL18376953 | 1.00 | IDH1 (1.00) | IDH1 | |
| SCHEMBL20397395 | 1.00 | IDH1 (1.00) | IDH1 | |
| SCHEMBL18376954 | 0.92 | IDH1 (1.00) | IDH1 | |
| SCHEMBL20397548 | 0.92 | IDH1 (1.00) | IDH1 | |
| SCHEMBL23280177 | 0.92 | IDH1 (1.00) | IDH1 | |
| SCHEMBL18376901 | 0.92 | IDH1 (1.00) | IDH1 | |
| SCHEMBL20414992 | 0.92 | IDH1 (1.00) | IDH1 | |
| SCHEMBL23280137 | 0.92 | IDH1 (1.00) | IDH1 | |
| SCHEMBL18376796 | 0.92 | IDH1 (1.00) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319945-B1 | 2-ARYL- AND 2-ARYLALKYL-BENZIMIDAZOLES AS MIDH1 INHIBITORS | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS (DE) | 2021-04-28 | — | — | EP | disclosed |