Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.74 |
| ▸ | POLA1 | P09884 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.71 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.61 |
| ▸ | VDR | P11473 | 4/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | OSBP | P22059 | 1/20 | 0.57 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | FGF1 | P05230 | 1/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26912121 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL4737651 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL26912125 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL19009192 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL19722006 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL17875190 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL12590990 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL16248053 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL10017479 | 1.00 | CDC25A (0.74) | CDC25APOLA1CYP2D6CYP2C19INPP5D | |
| SCHEMBL728827 | 0.92 | CDC25A (0.76) | CDC25APOLA1CYP2D6CYP2C19INPP5D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812392-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | Sage Therapeutics, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |