Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.51 |
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP1 | P63208 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711018 | 0.87 | CHRM4 (0.57) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL2325034 | 0.84 | FFAR4 (0.50) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL2331013 | 0.84 | NPC1 (0.49) | CHRM4SCD | |
| SCHEMBL1710740 | 0.83 | CHRM4 (0.48) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL2323704 | 0.81 | CHRM4 (0.50) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL344551 | 0.79 | CHRM4 (0.60) | CHRM4CHRM2 | |
| SCHEMBL1711361 | 0.79 | CHRM4 (0.54) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL14796956 | 0.78 | CHRM4 (0.51) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL1728839 | 0.76 | CHRM4 (0.52) | CHRM4CHRM2CHRM1CHRM5CHRM3 | |
| SCHEMBL1728738 | 0.76 | CHRM4 (0.50) | CHRM4CHRM2CHRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356108-B1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-10-15 | — | — | EP | disclosed |
| US-8716289-B2 | Carbamate derivatives of alkyl-heterocycles, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2014-05-06 | — | — | US | disclosed |
| CN-102216291-A | Carbamate derivatives containing alkyl-heterocycles, preparation and therapeutic use thereof | SANOFI AVENTIS | 2011-10-12 | — | — | CN | disclosed |
| EP-2356108-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055267-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-05-20 | — | — | WO | disclosed |