Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27478656 | 0.95 | PTGER4 (0.57) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL3998365 | 0.89 | PTGER4 (0.79) | PTGER4LNPEPERAP2KDM4EALDH1A1 | |
| SCHEMBL27110998 | 0.88 | PTGER4 (0.50) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL24900042 | 0.86 | PTGER4 (0.49) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL24900141 | 0.86 | PTGER4 (0.49) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL25734417 | 0.86 | PTGER4 (0.49) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL23286895 | 0.84 | PTGER4 (0.46) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL29491456 | 0.84 | KMT2A (0.46) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL20288191 | 0.84 | KMT2A (0.46) | PTGER4HDAC1LNPEPERAP2KDM4E | |
| SCHEMBL29825443 | 0.84 | KMT2A (0.46) | PTGER4HDAC1LNPEPERAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |