SCHEMBL2329474

SCHEMBL2329474

COC(=O)[C@H](CCSC)NC(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FNTA P49354 6/20 0.63
FNTB P49356 6/20 0.63
TDP1 Q9NUW8 2/20 0.63
KMT2A Q03164 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.56
CNR1 P21554 2/20 0.53
CNR2 P34972 2/20 0.53
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
TAS1R3 Q7RTX0 1/20 0.52
TAS1R1 Q7RTX1 1/20 0.52
CYP3A4 P08684 1/20 0.51
CYP2C19 P33261 1/20 0.51
PGGT1B P53609 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2329471 1.00 FNTA (0.63) FNTAFNTBTDP1KMT2AL3MBTL1
SCHEMBL2328137 0.90 FNTA (0.53) FNTAFNTBTDP1KMT2AL3MBTL1
SCHEMBL2328139 0.90 FNTA (0.53) FNTAFNTBTDP1KMT2AL3MBTL1
SCHEMBL2329537 0.88 FNTA (0.61) FNTAFNTBTDP1PGGT1B
SCHEMBL28813122 0.88 FNTA (0.59) FNTAFNTBTDP1KMT2AKDM4E
SCHEMBL2333712 0.88 FNTA (0.59) FNTAFNTBTDP1KMT2AKDM4E
SCHEMBL2327909 0.88 FNTA (0.52) FNTAFNTBTDP1KMT2AL3MBTL1
SCHEMBL2327912 0.88 FNTA (0.52) FNTAFNTBTDP1KMT2AL3MBTL1
SCHEMBL6772258 0.87 FNTA (0.66) FNTAFNTBTDP1KMT2AL3MBTL1
SCHEMBL629764 0.86 FNTA (0.65) FNTAFNTBTDP1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
CN-102215812-B Anti-wrinkle agents POLA CHEM IND INC 2014-09-10 CN disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed
WO-1998050030-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 FNTA 4644/4885FNTB 4431/4885TDP1 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.