Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL10651999 | 0.97 | TP53 (0.42) | TP53LMNAALDH1A1FFAR3ALDH2 | |
| SCHEMBL5406160 | 0.84 | — | — | |
| SCHEMBL42300 | 0.84 | — | — | |
| Dimethylamine SCHEMBL10879755 | 0.81 | FFAR3 (0.42) | LMNAALDH1A1FFAR3ALDH2MMP1 | |
| SCHEMBL4917666 | 0.81 | — | — | |
| SCHEMBL150702 | 0.81 | — | — | |
| SCHEMBL640077 | 0.81 | — | — | |
| SCHEMBL7155503 | 0.81 | — | — | |
| SCHEMBL672336 | 0.81 | — | — | |
| SCHEMBL7155785 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187543-B1 | POLYKETONE RESIN COMPOSITION HAVING EXCELLENT OIL RESISTANCE | HYOSUNG CHEMICAL CORP (KR) | 2021-05-12 | — | — | EP | disclosed |
| EP-3187544-B1 | POLYKETONE RESIN COMPOSITION HAVING OUTSTANDING WATER RESISTANCE | HYOSUNG CHEMICAL CORP (KR) | 2021-05-05 | — | — | EP | disclosed |
| WO-2020190018-A1 | MULTI-LAYERED TUBE COMPRISING POLYKETONE AND POLYOLEFIN | 효성화학 주식회사 | 2020-09-24 | — | — | WO | disclosed |
| US-20180162996-A1 | POLYKETONE RESIN COMPOSITION WITH EXCELLENT WEAR RESISTANCE | HYOSUNG CORPORATION (KR) | 2018-06-14 | — | — | US | disclosed |
| US-20170313820-A1 | POLYKETONE RESIN COMPOSITION HAVING EXCELLENT GAS BARRIER PROPERTIES | HYOSUNG CORPORATION (KR) | 2017-11-02 | — | — | US | disclosed |
| EP-3219744-A1 | POLYKETONE RESIN COMPOSITION WITH EXCELLENT WEAR RESISTANCE | Hyosung Corporation (KR) | 2017-09-20 | — | — | EP | disclosed |
| EP-3216818-A2 | POLYKETONE RESIN COMPOSITION HAVING EXCELLENT GAS BARRIER PROPERTIES | Hyosung Corporation (KR) | 2017-09-13 | — | — | EP | disclosed |
| EP-3187544-A2 | POLYKETONE RESIN COMPOSITION HAVING OUTSTANDING WATER RESISTANCE | Hyosung Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
| EP-3187543-A2 | POLYKETONE RESIN COMPOSITION HAVING EXCELLENT OIL RESISTANCE | Hyosung Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
| US-20170166743-A1 | POLYKETONE RESIN COMPOSITION HAVING EXCELLENT OIL RESISTANCE | HYOSUNG CORPORATION (KR) | 2017-06-15 | — | — | US | disclosed |
| US-20170158851-A1 | POLYKETONE RESIN COMPOSITION HAVING OUTSTANDING WATER RESISTANCE | HYOSUNG CORPORATION (KR) | 2017-06-08 | — | — | US | disclosed |
| EP-1894959-B1 | Process for producing polyketone | HYOSUNG CORP (KR) | 2011-08-17 | — | — | EP | disclosed |
| US-7803897-B2 | with improved catalytic activity and intrinsic viscosity; as a catalyst component, an organometallic complex comprising palladium acetate, 1,3-bis[bis(2-methoxy-5-methylphenyl)phosphino]propane; copolymerization of carbon monoxide and ethylene in a liquid medium in presence of abouve catalyst | HYOSUNG CORPORATION (KR) | 2010-09-28 | — | — | US | disclosed |
| EP-1942127-B1 | Process for preparing polyketone | HYOSUNG CORP (KR) | 2010-01-27 | — | — | EP | disclosed |
| EP-1942127-A1 | Process for preparing polyketone | Hyosung Corporation (KR) | 2008-07-09 | — | — | EP | disclosed |
| US-20080161531-A1 | Process for preparing polyketone | HYOSUNG CORPORATION (KR) | 2008-07-03 | — | — | US | disclosed |
| US-20080058494-A1 | Process for preparing polyketone | HYOSUNG CORPORATION (KR) | 2008-03-06 | — | — | US | disclosed |
| US-20080058493-A1 | Process for producing polyketone | HYOSUNG CORPORATION (KR) | 2008-03-06 | — | — | US | disclosed |
| EP-1894959-A1 | Process for producing polyketone | Hyosung Corporation (KR) | 2008-03-05 | — | — | EP | disclosed |
| EP-1894960-A1 | Process for producing polyketone | Hyosung Corporation (KR) | 2008-03-05 | — | — | EP | disclosed |