Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61827 | 0.87 | — | — | |
| SCHEMBL416451 | 0.87 | — | — | |
| SCHEMBL63056 | 0.87 | — | — | |
| SCHEMBL29906327 | 0.87 | — | — | |
| SCHEMBL29516751 | 0.87 | — | — | |
| Lithium Ion SCHEMBL5181106 | 0.75 | — | — | |
| SCHEMBL2301487 | 0.75 | — | — | |
| SCHEMBL6887900 | 0.75 | — | — | |
| SCHEMBL21436262 | 0.75 | — | — | |
| SCHEMBL18065727 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8408407-B2 | Knuckle formed through the use of improved external and internal sand cores and method of manufacture | BEDLOE INDUSTRIES LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-20120000877-A1 | Knuckle Formed Through The Use Of Improved External and Internal Sand Cores and Method of Manufacture | BEDLOE INDUSTRIES LLC | 2012-01-05 | — | — | US | disclosed |
| WO-2011082348-A1 | IMPROVED KNUCKLE FORMED THROUGH THE USE OF IMPROVED EXTERNAL AND INTERNAL SAND CORES AND METHOD OF MANUFACTURE | BEDLOE INDUSTRIES LLC (US) | 2011-07-07 | — | — | WO | disclosed |