Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2329906

COc1ccc2ccc(S(=O)(=O)N(CC(=O)NCc3ccccc3)[C@H]3CCN(Cc4csc(C(=N)N)c4)C3=O)cc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.66
F2 P00734 12/20 0.66
PLG P00747 1/20 0.66
PLAT P00750 1/20 0.66
PROC P04070 1/20 0.66
KLK6 Q92876 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2329189 0.94 F10 (0.65) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2331874 0.91 KLK6 (0.77) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2331871 0.91 KLK6 (0.77) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2330620 0.91 F10 (0.74) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2333295 0.90 F10 (0.78) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2326242 0.86 F10 (0.75) F10F2PLGPROCKLK6
Trifluoroacetic Acid SCHEMBL2328333 0.86 F10 (0.89) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2328337 0.86 F10 (0.89) F10F2PLGPLATPROC
Trifluoroacetic Acid SCHEMBL2335734 0.85 KLK6 (0.90) F10F2PLGPLATPROC
SCHEMBL2329422 0.85 F10 (0.59) F10F2PLGPLATPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP claimed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP claimed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO claimed
EP-0853618-B1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2011-08-17 EP disclosed
EP-0853618-A4 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE POULENC RORER PHARMA (US) 2000-03-15 EP disclosed
EP-0853618-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1998-07-22 EP disclosed
WO-1996040679-A1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N-[(AMINOIMINOMETHYL)PHENYLALKYL]-AZAHETEROCYCLYLAMIDE COMPOUNDS RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-12-19 WO disclosed