Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 17/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.64 |
| ▸ | FYN | P06241 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23299207 | 0.99 | MKNK1 (0.67) | MKNK1PIM1KCNH2FYN | |
| SCHEMBL16216094 | 0.91 | PIM1 (0.77) | PIM1KCNH2FYN | |
| SCHEMBL22421489 | 0.91 | PIM1 (0.64) | PIM1KCNH2FYN | |
| SCHEMBL16216065 | 0.91 | PIM1 (0.77) | PIM1KCNH2FYN | |
| SCHEMBL16216051 | 0.90 | PIM1 (0.77) | MKNK1PIM1KCNH2FYN | |
| SCHEMBL23299265 | 0.89 | PIM1 (0.79) | MKNK1PIM1KCNH2FYN | |
| SCHEMBL23299241 | 0.88 | PIM1 (0.80) | PIM1KCNH2FYN | |
| SCHEMBL16216052 | 0.88 | PIM1 (0.78) | PIM1KCNH2FYN | |
| SCHEMBL16216057 | 0.88 | PIM1 (0.80) | PIM1KCNH2FYN | |
| SCHEMBL18355905 | 0.88 | PIM1 (0.78) | PIM1KCNH2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |