Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.64 |
| ▸ | PIM2 | Q9P1W9 | 14/20 | 0.64 |
| ▸ | FLT3 | P36888 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216068 | 0.91 | PIM1 (0.78) | PIM1PIM2FLT3 | |
| SCHEMBL22421465 | 0.90 | PIM1 (0.62) | PIM1PIM2FLT3 | |
| SCHEMBL16216091 | 0.88 | PIM1 (0.78) | PIM1PIM2FLT3 | |
| SCHEMBL16216054 | 0.88 | PIM1 (0.79) | PIM1PIM2FLT3 | |
| SCHEMBL103791 | 0.87 | PIM1 (0.81) | PIM1PIM2FLT3 | |
| SCHEMBL16216067 | 0.86 | PIM1 (0.81) | PIM1PIM2FLT3 | |
| SCHEMBL19986965 | 0.83 | PIM1 (0.83) | PIM1PIM2FLT3 | |
| SCHEMBL19987011 | 0.81 | TGFBR2 (0.72) | PIM1PIM2FLT3 | |
| SCHEMBL4335504 | 0.79 | PIM1 (0.79) | PIM1PIM2FLT3 | |
| SCHEMBL16210821 | 0.78 | PIM1 (1.00) | PIM1PIM2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |