SCHEMBL23299568

SCHEMBL23299568

c1ccc(-c2ccc3c(c2)oc2cccc(-c4nc(-c5ccccc5)nc(-c5cccc(-n6c7ccccc7c7ccccc76)c5)n4)c23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
PDE10A Q9Y233 1/20 0.35
TP53 P04637 2/20 0.33
HPSE Q9Y251 3/20 0.32
HCRTR1 O43613 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
MAPK1 P28482 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24065301 1.00 ATM (0.35) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL23299590 0.98 ATM (0.35) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL26761378 0.96 ATM (0.35) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL24152733 0.96 KDM4E (0.37) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL24303455 0.95 KDM4E (0.33) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL26047273 0.95 PDE10A (0.34) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL20291025 0.95 PDE10A (0.35) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL20290930 0.95 PDE10A (0.35) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL21583554 0.95 KDM4E (0.36) ATMKDM4EL3MBTL1PDE10ATP53
SCHEMBL24574972 0.95 ATM (0.36) ATMKDM4EL3MBTL1TP53HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021080368-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-04-29 WO disclosed