Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.57 |
| ▸ | JAK1 | P23458 | 20/20 | 0.57 |
| ▸ | TYK2 | P29597 | 20/20 | 0.57 |
| ▸ | JAK3 | P52333 | 7/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23276598 | 1.00 | JAK2 (0.57) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276632 | 1.00 | JAK2 (0.57) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276946 | 0.90 | JAK1 (0.59) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23276945 | 0.90 | JAK1 (0.59) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23276743 | 0.86 | JAK2 (0.59) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276923 | 0.86 | JAK2 (0.59) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276745 | 0.86 | JAK2 (0.59) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276845 | 0.83 | JAK1 (0.69) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276700 | 0.83 | TYK2 (0.54) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276849 | 0.83 | TYK2 (0.54) | JAK2JAK1TYK2JAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |