Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.60 |
| ▸ | JAK2 | O60674 | 18/20 | 0.60 |
| ▸ | TYK2 | P29597 | 18/20 | 0.60 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 7/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | STAT1 | P42224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23277048 | 0.91 | JAK2 (0.54) | JAK1JAK2TYK2JAK3BTK | |
| SCHEMBL23276742 | 0.90 | JAK1 (0.53) | JAK1JAK2TYK2JAK3BTK | |
| SCHEMBL23276861 | 0.88 | JAK1 (0.51) | JAK1JAK2TYK2JAK3BTK | |
| SCHEMBL23299631 | 0.87 | JAK1 (0.61) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL23277043 | 0.86 | JAK1 (0.49) | JAK1JAK2TYK2JAK3BTK | |
| SCHEMBL23276622 | 0.85 | JAK2 (0.48) | JAK1JAK2TYK2JAK3BTK | |
| SCHEMBL23276934 | 0.84 | JAK2 (0.52) | JAK1JAK2TYK2JAK3KDR | |
| SCHEMBL23277052 | 0.84 | JAK1 (0.61) | JAK1JAK2TYK2JAK3 | |
| SCHEMBL23299629 | 0.84 | JAK1 (0.53) | JAK1JAK2TYK2JAK3BTK | |
| SCHEMBL23277050 | 0.83 | JAK2 (0.49) | JAK1JAK2TYK2JAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |