Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | GBA1 | P04062 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23300544 | 1.00 | CYP2D6 (0.60) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL29915599 | 1.00 | CYP2D6 (0.60) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL22927424 | 0.84 | CYP2D6 (0.60) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL23300547 | 0.83 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL23318121 | 0.83 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL23300546 | 0.83 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL30080216 | 0.83 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL2342350 | 0.83 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL24446594 | 0.83 | CYP2D6 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL29729337 | 0.82 | CYP3A4 (0.74) | CYP2D6SLC6A4KCNH2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4053103-B1 | EXPECTORANT COMPOUND AND PREPARATION METHOD AND USE THEREOF | HC SYNTHETIC PHARMACEUTICAL CO LTD (CN) | 2025-03-19 | — | — | EP | claimed |
| WO-2021082501-A1 | EXPECTORANT COMPOUND AND PREPARATION METHOD AND USE THEREOF | 华创合成制药股份有限公司 | 2021-05-06 | — | — | WO | claimed |
| CN-112745251-A | Compound for eliminating phlegm and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-05-04 | — | — | CN | claimed |
| CN-112745251-B | Compound for treating phlegm and preparation method and application thereof | 华创合成制药股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2021082501-A1 | EXPECTORANT COMPOUND AND PREPARATION METHOD AND USE THEREOF | 华创合成制药股份有限公司 | 2021-05-06 | — | — | WO | disclosed |
| CN-112745251-A | Compound for eliminating phlegm and preparation method and application thereof | 华创合成制药股份有限公司 | 2021-05-04 | — | — | CN | disclosed |